{"id":345,"date":"2020-02-16T10:56:18","date_gmt":"2020-02-16T05:26:18","guid":{"rendered":"https:\/\/medicineplexus.com\/?p=345"},"modified":"2020-02-16T10:56:18","modified_gmt":"2020-02-16T05:26:18","slug":"drugs-acting-on-potassium-channels","status":"publish","type":"post","link":"https:\/\/medicineplexus.com\/drugs-acting-on-potassium-channels\/","title":{"rendered":"Drugs acting on Potassium channels"},"content":{"rendered":"\n
Drugs acting on Potassium channels<\/strong><\/p>\n\n\n\n Ion Channels<\/strong><\/p>\n\n\n\n There are four major classes of potassium channels:<\/p>\n\n\n\n Calcium-activated potassium channel<\/strong> – open in response to the presence of calcium ions or other signalling molecules.<\/p>\n\n\n\n Inwardly rectifying potassium channel<\/strong> – passes current (positive charge) more easily in the inward direction (into the cell).<\/p>\n\n\n\n Tandem pore domain potassium channel<\/strong> – are constitutively open or possess high basal activation, such as the “resting potassium channels” or “leak channels” that set the negative membrane potential of neurons.<\/p>\n\n\n\n Voltage-gated potassium channel –<\/strong> are voltage-gated ion channels that open or close in response to changes in the transmembrane voltage.<\/p>\n\n\n\n Modulators of K channels<\/strong><\/p>\n\n\n\n Blockers<\/strong><\/p>\n\n\n\n